Dear MEL staff, could you please advise me? Our agency is launching an anti-drug program, but it is almost impossible to conduct randomization. Is there any good alternative for that?

Glad to hear!

Wow, it is the first time I hear of this strategy. Thank you so much for the advice!

You may try using Propensity Score Matching (PSM), where participants in the intervention are matched with similar people who do not receive the intervention. They can be matched on several different criteria, including demographics (age, sex, educational level, socioeconomic status) or other characteristics (e.g., service use, employment history).