Does ddietary change have benefits for successful aging?

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Diet and nutrition-based interventions are the most frequently studied strategies for extending the life-span in animal models of aging. In humans, studies have demonstrated that high calorie diets and obesity are risk factors for dementia. As such, it is not surprising that there has been an increase in the empirical attention given to dietary interventions. Of note, the findings supporting the use of dietary supplements have been mixed. For example, diets supplemented with folic acid, omega-3 fatty acids, and antioxidants have been associated with better cognitive functioning, while other supplements such as ginkgo biloba and vitamin D have not shown significant benefit for cognition. On the other hand, dietary patterns such as the Mediterranean diet, which includes high consumption of fruits and vegetables, high ratio of polyunsaturated to saturated fats, and foods with low glycemic load, have been shown to be associated with reduced depressive symptoms and lower risk for cognitive impairment.